![]() 1, 2 While the etiology of this condition is not fully elucidated, recent research suggests that an increase in lens rigidity is the primary causative mechanism. Presbyopia is hypothesized to be caused by either a weakening of the ciliary muscles or a loss of lens elasticity preventing focal point change. Presbyopia is a common, age-related vision disorder characterized by a progressive inability to focus on near objects. This review highlights the need for effective, broadly accessible, non-invasive presbyopic treatment options. However, current treatment options for presbyopia, which include glasses, contact lenses and surgery, mostly manage the symptom of blurred near vision, without addressing the underlying cause of the condition. We discovered that presbyopia is typically diagnosed around 50 years of age, with optometrists being the major providers of vision correction. Presbyopia onset may also be influenced by an individual’s distance glasses prescription. Our research found that the onset of presbyopia may be earlier in women and in individuals who live closer to the equator. Presbyopia is an age-related decline in the ability to focus on near tasks, thought to be caused by a loss of flexibility, increase in size and hardening of the lens and/or the muscle fibers surrounding the lens inside the eye. This review was carried out to i) explore available evidence on the causes and risk factors of presbyopia, ii) summarize how the condition is currently diagnosed and managed, including residual unmet needs and iii) provide an overview of potential future treatment options that are currently in development. The data reviewed herein reveals significant gaps in the provision of vision correction for this common condition, with a paucity of effective, non-invasive treatment options broadly accessible to presbyopic individuals. The diagnosis pathway and patient journey in presbyopia are outlined, and various treatment options are analyzed. ![]() In this narrative review, available evidence on presbyopia prevalence, quality of life impact and risk factors are described, with a focus on observational studies in non-clinical settings. Non-invasive therapies with novel mechanisms of action are currently being investigated these include miotic agents and UNR844, a lipoic acid choline ester. While patients undergoing surgery report satisfactory outcomes post-operatively, many of them eventually require reading glasses. ![]() ![]() Other corrective methods involve surgical interventions that modify the optics of the cornea, replace the crystalline lens, or attempt to restore active accommodation. Contact lens options can be difficult to maintain due to the development of age-related dry eye symptoms and reduced manual dexterity. Progressive or bifocal spectacles are associated with peripheral blur, a restricted visual field and impaired depth perception, which have been linked to an increased risk of falls in the elderly. Presbyopia represents an area of considerable unmet need due to its rising prevalence worldwide as the population ages, the high proportion of under-treated individuals in some parts of the world, and the limitations of currently available corrective methods. If uncorrected or under-corrected, presbyopia can significantly impact patients’ quality of life. Presbyopia is a common age-related vision disorder characterized by a progressive inability to focus on near objects.
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![]() When cannabis plants are left to mature for too long, there can be a decrease in the amount of THC and an increase in CBN, which reduces the psychoactive effects of the plant and enhances its sedative properties. There are too many clear and transparent trichomes.There are too many vertically grown white pistils.Signs That Indicate You Harvest Too Early Additionally, harvesting too early can result in lower amounts of CBN found in the plant as well. If you harvest cannabis too early, the trichomes may not have developed enough THC and other cannabinoids, which can result in a weaker high effect. To make it easier to understand, strains with higher levels of THC tend to produce a more uplifting and energizing high, while strains with higher levels of CBN tend to be more calming and relaxing.Īs the cannabis plant matures, THC levels generally increase while CBN levels increase due to the degradation of THC. The ratio of THC to CBN can affect the overall experience and effects of cannabis. THC is primarily responsible for the euphoric, psychoactive effects of cannabis, while CBN is known for its sedative properties. To answer this question, it’s necessary to figure out two main cannabinoids, THC (delta-9-tetrahydrocannabinol) and CBN (cannabinol), which are two major compounds that produce the effects of each strain. By examining the trichomes, you can ensure that you harvest your cannabis plants at the right time for the desired effect and flavor. Also, different strains may have varying maturation times. It is essential to monitor the trichomes regularly, as the ripening process can happen quickly before you realize it. When 80-90% of the trichome heads have become cloudy, it indicates that the plant is ready for harvest, and the potency of the buds will be at its peak with the highest THC and CBD.Initially, the trichomes are clear and glassy, but they turn cloudy or opaque as the plant grows into the next growth stage.By focusing on the trichomes with the ball on top, you can determine when they have reached their highest levels of THC and CBD. Since they do not impact the potency, so simply ignore them. You may also see hair-like trichomes without the mushroom head. Spot the trichomes that look like small mushrooms with a ball on top.Therefore, you’d better prepare a jeweler’s loupe or other magnifiers for examining the trichomes. However, it can be difficult to spot them clearly with the naked eye. To identify if the trichomes are ripened enough, look for the color and shape.Check the guideline below to know how to tell when cannabis is ready for harvest from the trichomes. ![]() Mark a Card: (Both Mac & Windows) Keep track of important cards that need extra attention. My question is, if I am studying a particular subject (ex. Suspend a Card: - (Both Mac & Windows) If you stumble upon a card thats not relevant or needs to be reevaluated later, use this shortcut. Hello Im a new follower on this subreddit but I am long time anki user for a long time. suspend some sub-decks within it so that it doesn't show up till you're. Here are some additional shortcuts that can boost your productivity while using Anki. Toggle suspend or unsuspend cards: CTRL+A: Select all cards in Anki while browsing: CTRL+SHIFT+P: Switch profile: CTRL+SHIFT+I : Import: CTRL+E : Export: CTRL+Q: Exit: CTRL+Z: CTRL+Z to undo or return to the previous card /. Note that in statistics on Anki Desktop, buried is. Search for suspended cards: is:suspended. A buried card is only buried for a day, a suspended card is suspended until you unsuspend it. Idk if i was the only one who was just unsuspending cards and not making separate decks when i watch a boards and beyond video (or whatever third party resource you use) but this has really helped me feel less overwhelmed and work on my cards throughout the day. And a good source for Anki decks is reddit or other. A card can be buried due to related cards (if a card is Basic (and reversed), reviewing the Basic card will bury the reverse) A card can be buried manually. ![]() 150+ cutscenes, most with choices, and most that link up to others for at least 300+ variations of cutscenes 20+ hours of voicework by 90+ voice actors, all of which have to be given voice direction and have their audio cut up and arranged for each character, then equalized volume-wise, per cutscene This is again, one of the best examples of it most of the other animations end up horribly bugged.Ĭlick to expand.We plan to fix most of the bugs before release that's what the 2 extra months is for.Īlso, while I love Vosmug's stuff and we've worked together, the amount of content in FF is probably bigger than the majority of non AAA games, and even some AAA games too. which means even with this, we'd be sacrificing quality, as in, the original intent of the feel of the animation. ![]() The thrusts don't look as soft, but they still feel somewhat softer than the original. The wings don't have as much of an issue, but the tail is still distorted. The thrusts still appear soft, too.Īnd here's a 20 FPS version, just to compare, again with RIFE The animation also feels very "soft" it looks more like he's just sort of lightly gliding his pelvis back and forth, not having rough sex.Ī 40 FPS version with RIFE: the wings look a little bit better, as does the tail, but they still both look janky. The original, above it has weight to it, impact, the thrusts have solid "oomph" to them.Ī 40 FPS version (as the original is 10 FPS, so this is 4x) with DAIN the wings and the tail look janky, to say the least, not something that looks good at all. Here's a few examples (and these are some of the best ones we could get) If there were a way to make it genuinely hand-draw pixel art animation frame by frame with the interpolation like what our artist is doing now, then we'd be for it, but as it is, the technology still has a way to go. It gives off a "Johnny Test Flash Animation" vibe and ruins the general feel of the aesthetic we're going for. It especially looks bad when you have characters with our cartoony-ish proportions, and even worse when it comes to different positions where body parts are hidden and the program can't figure it out.Īnd, even if it did work perfectly, interpolation just looks sloppy, to be honest. Cleaning up the sprite while keeping the "interpolated frames aesthetic" consistent would take about as long for our artist as just doing the extra frames themselves in their own style. Pixel art usually looks pretty awful with them we've tried, with lots of different programs and websites. Java and OpenJDK are trademarks or registered trademarks of Oracle and/or its affiliates.Click to expand.These only work well with certain types of art. Fragments: Past, present, and future (Android Dev Summit '19)Ĭontent and code samples on this page are subject to the licenses described in the Content License.Single Activity: Why, when, and how (Android Dev Summit '18).Navigate between fragments using animations.Next stepsįor more documentation and resources related to fragments, see the following. The logic necessary to manage its own UI. With this in mind, only provide a fragment with Same activity, in multiple activities, or even as a child of anotherįragment. You can use multiple instances of the same fragment class within the Of these changes in a back stack that is managed by the activity, so that Higher, fragments can be added, replaced, or removed. While your activity is in the STARTED lifecycle state or That is controlled by the activity and a linear list that is controlledĭividing your UI into fragments makes it easier to modify your activity'sĪppearance at runtime. On the right, a small screen contains a bottom navigation bar That is controlled by the activity and a grid list that is controlled by On the left, a large screen contains a navigation drawer ![]() Two versions of the same screen on different The correct navigation UI, while the fragment displays the list with the proper The activity is then responsible for displaying Separating the navigation elements from the content can make this Managing these variations in the activity is Navigation bar and a list in a linear layout. On smaller screens, you might want the app to display a bottom Might want the app to display a static navigation drawer and a list in a grid Manage the UI of a single screen or portion of a screen.Ĭonsider an app that responds to various screen sizes. Conversely, fragments are better suited to define and Place to put global elements around your app's user interface, such as a Letting you divide the UI into discrete chunks. Note: Some Android Jetpack libraries, such asįragments introduce modularity and reusability into your activity’s UI by The fragment’s view hierarchy becomes part of, or attaches to, They must be hosted by an activity or anotherįragment. Layout, has its own lifecycle, and can handle its own input events.
![]() You'll sit on a chair with a soft clip on your nose.There are different ways to do each type of lung function test. What happens during lung function testing? Other names: pulmonary function tests, PFTs Your health care provider may order one or more lung function tests, depending on the reason you need to be tested. Cardiopulmonary (heart and lung) exercise test (CPET).There are different types of tests that measure how well your lungs work when you are active, including: This test measures how well your lungs deliver oxygen to your blood from the air you breathe. It also measures the amount of air that remains in your lungs after you exhale as much as you can. This test is the most accurate way to measure the amount of air your lungs can hold. Lung volume test, also called as body plethysmography.A spirometry test measures how much air you breathe out and how fast you can blow air out of your lungs. This lung function test is used the most. Your airways are the parts of your body that carry air to your lungs, including your nose, throat, trachea (windpipe), and bronchial tubes that connect your windpipe to each lung. Lung function tests also help check the health of your airways. How well your lungs absorb oxygen from the air you breathe and move it into your blood. ![]() How well you move air in and out of your lungs when you breathe.The mouthpiece is connected to a device that makes different types of measurements, such as: Most of them involve breathing through a mouthpiece. ![]() There are many types of lung function tests. They may be used with other tests and information to help diagnose and monitor certain lung diseases. These tests are also called pulmonary function tests, or PFTs. Lung function tests are a group of tests that check how well your lungs are working. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. contact Steam Support for account recovery even if someone has changed the accounts email address, password, and phone number. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. The cookies is used to store the user consent for the cookies in the category "Necessary". The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". The cookie is used to store the user consent for the cookies in the category "Analytics". These cookies ensure basic functionalities and security features of the website, anonymously. Necessary cookies are absolutely essential for the website to function properly. Whether you have forgotten your username or password for your Steam account, it is very easy to change or reset it. It is the account name that is visible on all the game stats on the Steam site. In fact, it is asking for your Steam account username. This results in login failure as Steam is not asking for your email address or phone number.
![]() These two collections of advanced software instruments and effects not only give you a wealth of sound to choose from – they also fire up your imagination. ![]() Unlock the full potential of your S-Series keyboard by combining it with the worldwide industry-standard instrument and effect suites for production, performance, and sound design. If you are purchasing, or already own an S-Series keyboard, you qualify for special pricing on KOMPLETE 10 and KOMPLETE 10 ULTIMATE. You can even use the keyboard in standalone mode to control your favorite hardware – in the studio or on stage. Use the Controller Editor to adjust touch strip behavior, configure keyboard splits with Light Guide visual feedback, and create custom templates. Send MIDI to hardware synths and access software instruments and external gear from one controller – a great way to use the arpeggiator. Record the output of KOMPLETE KONTROL’s Smart Play features directly into a DAW for further tweaking. Map chords simply by selecting mode and inversion, or by loading up a chord set – ready-to-play progressions to inspire and augment your own compositions. It will even re-map ‘wrong’ notes so you’re always in tune.Īctivate chord mode and create a rich harmonic performance by playing single keys. See notes of the currently selected scale lit on the Light Guide, and set virtually any musical scale to the white keys. The integrated scale mapping features give you instant access to a world of melody. Best of all, the output of the arpeggiator can be recorded as individual MIDI notes for post-performance editing. The eight controller knobs manage parameters such as direction, rate, rhythm, patterns, and variations. KOMPLETE KONTROL’s arpeggiator turns one note into a full musical performance. Or create instant shifts with different stepped settings. They can mimic the behavior of pitch and mod wheels, and physical objects like springs and bouncing balls for interesting modulation curves. In chord or arpeggiator mode, all triggered notes light up when you press a key, so you always know exactly what’s happening.ĭeliver dynamic performances with two ultra-sensitive touch strips. ![]() In scale mode, notes in the scale light up on the keyboard, with the root lit even brighter – perfect if you aren't a trained keyboard player. Use the Light Guide to identify drum cells, key switches, phrases, and more at a glance – play every KOMPLETE Instrument in full color. The result: You see exactly what you’re editing directly on the hardware, whether it’s EQ in kHz or the exact frequency of a filter cutoff – without any setup time. All essential parameter names and values load instantly on the Clear View display, and are intuitively grouped into pages. Each KOMPLETE Instrument was mapped in-house by Native Instruments’ sound designers. Native Map® technology guarantees you don't need to worry about mapping KOMPLETE Instrument parameters ever again. The keyboard and all its features remain fully functional even when in Browse mode – never stop performing. Just press the Browse button, turn the push encoder to select your instrument, choose a sound, and go. Search for sounds across all KOMPLETE Instruments using musical tags and keywords. And what’s more, the NKS version of an instrument will be a free update for existing owners.ĭig deep into thousands of sounds with ease, thanks to the unified browsing workflow of KOMPLETE KONTROL – limitless inspiration in a single plug-in. NKS instruments can access the Light Guide, Smart Play features, and the full creative potential of KOMPLETE KONTROL. This means that even instruments not built by NI can be fully integrated in the KOMPLETE KONTROL and MASCHINE browsers, with instrument parameters intelligently mapped straight out of the box. It allows VST and KONTAKT instrument developers to integrate their plug-ins with KOMPLETE KONTROL and MASCHINE at the same deep level as KOMPLETE Instruments. NKS is Native Instruments’ extended plug-in format that opens up the KOMPLETE KONTROL system. KOMPLETE KONTROL continues its evolution with Native Kontrol Standard® (NKS). VST support opens the gates to your entire software instrument library. It introduces Native Kontrol Standard® (NKS) – a new plug-in format which unlocks KOMPLETE KONTROL so that third-party instruments can access the Light Guide, Smart Play features, and more – with all instrument parameters intelligently mapped. The KOMPLETE KONTROL software is constantly evolving, and the latest software update is the biggest yet. ![]() The KOMPLETE KONTROL S-Series combines smart, elegantly designed keyboards with advanced control software to form a fully integrated centerpiece for studio and stage – matchless control over all your software instruments from one award-winning keyboard. 61-key MIDI controller with NKS technology for superior plug-in integration. ![]() Re: "Trust the OS" - If only it were that simple. It would be a good idea to have separate memory pools with no-access pages between them to segregate different types of in-process data from buffer overruns, but you'd pretty much have to write your own allocator for that purpose too. The big issue here is simply not validating the received PDU (which could simply be random data, even if not malicious). And of course OpenSSL runs on a wide variety of platforms and malloc performs rather differently across all of them. Applications often keep several separate memory pools and libraries often expect (or at least allow) the calling application to do their memory allocation for them. There's no way malloc could "know" what the best thing to do would be in every circumstance. And OpenSSL isn't even an application, it's a library used by applications which use memory for other things and might not want OpenSSL to get memory on a first-come-first-served basis. Using malloc for every PDU you received (for example) would be madness. Memory allocation is always going to be a problem because the "right" strategy depends on the application. "Trust the OS" - If only it were that simple. Ask how quickly microsoft/IBM/Oracle/Sybase come up with fixes to such problems. In any event, the patch was out the same day it was discovered and people were patching their SSL code straight away. ![]() So holding up the whole of the FOSS community to ridicule, and the author of this code specifically, is pointless. There is no doubt that Heartbleed is a big bug. These are things that need to be done fast and efficiently. Context Swaps, Process Creation, memory paging, device IO. Very carefully controlled ways of ignoring bounds checking are used so that your PC responds fast, at the speed you want. The second problem is that, in the kernel of an O/S, especially in Unix/Linux type of O/S's, there are many places where bounds checking is just inappropriate. The first problem is that at compile time the bounds are not known. ![]() So yeah, modern Linuxes give you lots of cool tools, but they're not compiled in by default.Ĭ is still my favorite programming language after all these decades, but most people really shouldn't be allowed to use it, certainly not without extensive oversight of anything security-critical.ĪC suggested he is not a coder drone and proposes that bounds checking be done in the compiler. The reason the memory of the dead objects wasn't zeroed on release is that, by default, OpenSSL keeps its own pool of memory and doesn't bother using malloc() very often (because on some systems, that might be slow, which would make managers sad), so OpenSSL doesn't call free() when it's done with those objects, and therefore if you've got a malloc()/free() system that has extra protection, like zeroing stuff or putting guard pages after chunks of memory to keep you from running off the ends, it doesn't waste time doing that. It's able to grab whatever 64KB off the heap is near the object it's supposed to be able to ask for, so that can include memory from live or dead objects, because C doesn't stop you from shooting yourself in the foot by running off the end of an array. No one programming technique is appropriate for all cases and attempting to use one across all or to use the wrong technique is utterly stupid. Some things are appropriate implemented one way, some another. If you had an understanding about just how much more processor resources (memory and CPU cycles) are consumed by managed code than unmanaged code then you would understand. ![]() The lower level the API the less appropriate it is that it is implemented using "managed" code. This kind attitude to coding is exactly why many current applications and indeed operating systems are so staggeringly inefficient and slow compared to the equivalent of even a few years ago despite the hardware being orders of magnitude faster. SURE I BROKE MY NECK A FEW TIMES, BUT IT'S NOT GONNA HAPPEN AGAIN. THIS ZIMMER FRAME REALLY GETS ME THERE FASTER, I JUST HAVE TO BE CAREFUL WHEN GOING DOWNSTAIRS. Writing in C means you have to be much more careful FROM THE EIGHTIES! Well, already in 1984: The Lilith That efficiency is achieved by working as close as possible to the "bare metal" - And C gets you there.īOLD TALK. System libraries usually need to be implemented in the most efficient possible way. Re: This attitude is not the key to success It’s simply sliced fresh nectarines, tossed with a handful of ingredients and layered on top of the pastry. There’s no pre-cooking involved, so the filling for this summer dessert couldn’t be easier. How to make the necterine blueberry galette filling ![]() Essentially, they’re ugly-beautiful, so you won’t need to fuss with pre-baking, fancy latticework, or weaving. ![]() ![]() Not only that, they’re meant to be rustic. Galettes are a perfect introduction to pastry, as they’re very easy to make. The word “galette” roughly translates to “little flat cake,” in French. You can assemble it ahead of time and then pop it in the oven to cook just before you want to serve it.Ī galette is a rustic French pie made by rolling the pastry into a large circle, filling it with fruit or a savory filling and then rolling the edges of the pastry onto the filling before baking it directly on the baking sheet rather than in a pie pan.
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